【摘要】Osteoarthritis (OA) is a chronic, debilitating disease that is the leading cause of disability and functional limitations in adults1-3. It is estimated that 15.8 million Americans between the ages of 25 and 74 have moderate to severe OA4. The most common symptoms of OA are joint pain, stiffness, and functional limitations. Previously, osteoarthritis was thought to be a result of "wear and tear" on the joints and physical activity was not an encouraged treatment. Now, it has become widely recognized that regular physical activity may benefit people with OA and may be a cost-effective treatment option for managing OA, symptoms such as reducing pain, improving muscle strength, and improving balance5,6. Recent self-report findings indicate that only 18% of men and 14% of women aged 65-74 achieve the physical activity recommendations of ≥ 30 minutes on at least 5 days a week7-9. Previous research that examines physical activity levels and relevant outcomes in individuals with knee OA are limited due to inadequate measurement tools and differences in study design. Objectively assessing physical activity habits in this population will help in the prescription of more beneficial treatment options.;The purpose of this study is to objectively assess the physical activity habits of older adults with knee OA; and to examine the relationship between physical activity and OA symptoms, such as functional limitations and pain. One-hundred and sixty participants (a sub-set of participants from the Intensive Diet and Exercise for Arthritis (IDEA) trial) wore an accelerometer for at least 4 days of 10 hours, which evaluated the number of steps/day, physical activity energy expenditure/day (PAEE), minutes of light physical activity (LPA), and minutes of moderate - vigorous intensity physical activity/day (MVP/VPA). Pearson correlations and manual step-wise regression analyses were used to examine the relationships between physical activity and physical function and pain in older adults with knee OA.;Results show that the total steps/day was 6209 (1459-15,949 steps) and PAEE averaged 237 + 124 (33-790) kcal/day. Total steps/day, PAEE, and minutes of MPA/VPA tended to be lower in individuals who were older. Being female was associated with less PAEE. There was a positive association between being white and steps/day, PAEE, minutes of LPA, and minutes of MPA/VPA. A higher SPPB score, which is indicative of greater lower extremity function, was associated with minutes of MPA/VPA. PA habits in this population were below the public health recommended levels. Participants who were more physically active in terms of total steps/day and PAEE had better overall physical function than those who achieved fewer total steps/day.
【摘要机译】骨关节炎（OA）是一种慢性衰弱性疾病，是成年人1-3残疾和功能受限的主要原因。据估计，年龄在25至74岁之间的1,580万美国人患有中度至重度OA4。 OA最常见的症状是关节疼痛，僵硬和功能受限。以前，骨关节炎被认为是关节“磨损”的结果，体力活动不鼓励治疗。现在，人们已经广泛认识到，定期进行体育锻炼可以使OA患者受益，并且可能是治疗OA，减轻疼痛，改善肌肉力量和改善平衡等症状的经济有效的治疗方法5,6。最近的自我报告发现表明，年龄在65-74岁之间的男性中只有18％和14％的女性在每周至少5天的7天内达到了≥30分钟的体育锻炼建议。由于测量工具不足和研究设计的差异，以前检查膝部OA患者身体活动水平和相关结局的研究有限。客观评估该人群的体育锻炼习惯将有助于开出更多有益的治疗方案。本研究的目的是客观评估患有膝关节炎的老年人的体育锻炼习惯；并检查身体活动与OA症状（例如功能受限和疼痛）之间的关系。一百六十名参与者（关节炎强化饮食和锻炼（IDEA）试验的参与者的子集）佩戴了加速度计，持续了至少10天的4天（共10个小时），评估了每天的步数，体力活动能量每天的支出（PAEE），轻度的体育活动（LPA）分钟和中度至剧烈强度的体育活动/天（MVP / VPA）分钟。皮尔逊相关性和人工逐步回归分析用于检查老年人膝关节OA的身体活动与身体机能与疼痛之间的关系;结果表明，每天总步数为6209（1459-15,949步），平均PAEE 237 + 124（33-790）kcal /天。每天的总步数/天，PAEE和MPA / VPA的分钟数往往较低。女性是与较少的PAEE相关联的。白人与步数/天，PAEE，LPA分钟和MPA / VPA分钟之间存在正相关。 SPPB得分越高，表明下肢功能越强，与MPA / VPA的分钟数相关。该人群的PA习惯低于公共健康推荐水平。在每天总步数和PAEE方面较活跃的参与者比每天总步数较少的参与者的整体身体功能更好。
【作者单位】Wake Forest University.;